Expert Advise

Your complete guide to understanding dose changes for weight loss injections — what to expect, how to manage side effects, and when to seek medical support.

What to Expect When Changing Dose

All weight loss medications are prescribed at a low dose to start with. You’ll then gradually increase your dose when you and your clinician agree you’re ready.

This process is called titration. It gives your body time to adjust and helps reduce side effects.

Three Key Takeaways:
  • Everyone must start low and increase gradually for safety.
  • Higher doses often improve results — but you don’t have to reach the highest dose.
  • Side effects usually appear or worsen temporarily after increasing.

How to Use Your New Dose

You will still inject once per week, on the same day and time, using the same pen device.

The only exception is Wegovy 7.2mg, which currently requires three 2.4mg injections at once.

When is the Best Time to Change Dose?

The minimum gap between increases is four weeks.

The best time to increase is when you:

  • Have time off work or can work from home
  • Have no important social events
  • Are not travelling
  • Have access to supplies and bathroom facilities

Benefits of Increasing Your Dose

  • Stronger appetite suppression
  • Reduced cravings
  • Better portion control
  • Feeling fuller for longer
  • More noticeable weight loss

Common Temporary Side Effects

  • Nausea
  • Diarrhoea
  • Constipation
  • Heartburn
  • Indigestion
  • Bloating
  • Vomiting

These typically resolve within a few days.

When to Speak to a Doctor

Seek immediate medical attention if you experience:
  • Severe abdominal pain spreading to shoulder or back
  • Yellowing of the eyes
  • Swelling of face, lips, or throat
  • Difficulty breathing
Call emergency services immediately if severe.

Frequently Asked Questions

Do you lose more weight on higher doses?
Yes. Most people experience greater weight loss as appetite suppression increases over time.
Does increasing your dose make you tired?
Fatigue can occur temporarily but typically resolves within a few days.
Can you switch to a lower dose?
Yes. Always speak to your prescriber to determine the most appropriate dose.
Book Consultation